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FDA imavomereza kuyesa kwachipatala - kuwunika mphamvu ya kusuta chamba chachipatala pochiza post-traumatic stress disorder (PTSD) mwa omenyera nkhondo

11-26

Pambuyo pazaka zopitilira zitatu, ofufuza akukonzekera kukhazikitsa mayeso odziwika bwino azachipatala omwe akufuna kuwunika momwe kusuta chamba chachipatala kuchiza matenda a post-traumatic stress disorder (PTSD) mwa omenyera nkhondo. Ndalama za kafukufukuyu zimachokera ku msonkho wochokera ku malonda a chamba ku Michigan.
Multidisciplinary Association for Psychedelic Drug Research (MAPS) idalengeza sabata ino kuti US Food and Drug Administration (FDA) yavomereza kafukufuku wagawo lachiwiri, lomwe MAPS adafotokoza m'mawu atolankhani ngati "kafukufuku wosasinthika, woyendetsedwa ndi placebo wa asitikali 320 opuma pantchito. ogwira ntchito omwe adasuta chamba ndipo anali ndi vuto laling'ono kapena loopsa la posttraumatic stress disorder.
Bungweli linanena kuti kafukufukuyu "akufuna kufufuza kuyerekezera komwe kulipo pakati pa kutulutsa mpweya wambiri wa THC zouma zouma zouma ndi cannabis ya placebo, ndipo mlingo watsiku ndi tsiku umasinthidwa ndi omwe akutenga nawo mbali." Kafukufukuyu akufuna kuwonetsa momwe amamwa mowa omwe achitika m'dziko lonselo, komanso kuphunzira "kugwiritsira ntchito kwenikweni kwa cannabis, kuti amvetsetse mapindu ake ndi kuopsa kwake pochiza matenda obwera chifukwa cha zoopsa."
MAPS adanena kuti ntchitoyi yakhala ikukonzekera kwa zaka zambiri ndipo inanena kuti panali zovuta zambiri zomwe anakumana nazo popempha chilolezo cha kafukufuku kuchokera ku FDA, zomwe zinathetsedwa posachedwa. Bungweli lidati, "Pambuyo pazaka zitatu zakukambirana ndi a FDA, lingaliro ili likutsegula khomo la kafukufuku wamtsogolo wokhudza chamba ngati njira yachipatala ndikubweretsa chiyembekezo kwa mamiliyoni a anthu.
Kutulutsa kwa atolankhani a MAPS akuti, "Poganizira kugwiritsa ntchito chamba pochiza matenda obwera chifukwa cha zoopsa, zowawa, ndi zovuta zina zathanzi, izi ndizofunikira pakudziwitsa odwala, opereka chithandizo chamankhwala, ndi ogula achikulire, koma zoletsa zomwe zapangitsa kuti zikhale zomveka. kafukufuku wokhudzana ndi chitetezo ndi mphamvu ya zinthu za chamba zomwe nthawi zambiri zimadyedwa m'misika yoyendetsedwa ndizovuta kwambiri kapena zosatheka.
MAPS inanena kuti pazaka zambiri, idayankha makalata asanu oyimitsidwa azachipatala ochokera ku FDA, omwe alepheretsa kafukufukuyu.
Malinga ndi bungweli, "Pa Ogasiti 23, 2024, MAPS adayankha kalata yachisanu ya FDA yokhudza kuyimitsidwa kwachipatala ndipo adapereka pempho lovomerezeka lothetsera mikangano (FDRR) kuti athetse kusamvana komwe kukuchitika ndi dipatimentiyi pazinthu zinayi zazikuluzikulu": " 1) mlingo wa THC woperekedwa wa mankhwala a Fried Dough Twists, 2) kusuta ngati njira yoyendetsera, 3) fumigation yamagetsi ngati njira oyang'anira, ndi 4) kulemba anthu omwe sanayesepo chithandizo cha cannabis. "
Wofufuza wamkulu wa kafukufukuyu, katswiri wazamisala Sue Sisley, adati kuyesaku kuthandizira kumveketsa bwino kuvomerezeka kwa sayansi kogwiritsa ntchito chamba chachipatala kuchiza matenda obwera pambuyo povulala. Ngakhale kuchulukirachulukira kwa chamba ndi odwala omwe ali ndi vuto la post-traumatic stress komanso kuphatikizika kwake m'mapulogalamu ambiri a chamba chamankhwala m'maiko ambiri, adanenanso kuti pakadali pano palibe chidziwitso chozama kuti athe kuwunika momwe chithandizochi chikuyendera.

chamba
Sisley adati m'mawu ake: "Ku United States, mamiliyoni aku America amawongolera kapena kuchiza zizindikiro zawo mwa kusuta kapena kugwiritsa ntchito chamba chamankhwala pamagetsi. Chifukwa chosowa chidziwitso chapamwamba chokhudzana ndi kugwiritsa ntchito chamba, zambiri zomwe zimapezeka kwa odwala ndi owongolera zimachokera ku chiletsocho, ndikungoyang'ana zoopsa zomwe zingachitike popanda kuganizira za chithandizo chomwe chingachitike. ”
M'zochita zanga, odwala akale adagawana momwe chamba chachipatala chingawathandizire kuthana ndi zovuta zapambuyo pazovuta zamavuto kuposa mankhwala azikhalidwe, "adatero. Kudzipha kwa ma Veterans ndivuto lalikulu laumoyo wa anthu, koma ngati tipanga ndalama pakufufuza njira zatsopano zochiritsira zomwe zimayika moyo pachiwopsezo monga vuto la post-traumatic stress disorder, vutoli litha kuthetsedwa.
Sisley adanena kuti gawo lachiwiri la kafukufuku wachipatala "lidzapanga deta yomwe madokotala ngati ine angagwiritse ntchito kupanga mapulani a chithandizo ndikuthandizira odwala kuwongolera zizindikiro za vuto la post-traumatic stress disorder.
Allison Coker, wamkulu wa kafukufuku wa cannabis ku MAPS, adati a FDA adatha kukwaniritsa mgwirizanowu chifukwa bungweli lidati lilola kupitiliza kugwiritsa ntchito chamba chachipatala chomwe chili ndi malonda omwe ali ndi THC gawo lachiwiri. Komabe, chamba chamagetsi chamagetsi chimakhalabe chokhazikika mpaka a FDA azitha kuwunika chitetezo cha chipangizo chilichonse choperekera mankhwala.
Poyankha madandaulo apadera a FDA okhudzana ndi kulemba anthu omwe sanalandirepo chithandizo cha chamba kuti achite nawo maphunziro azachipatala, MAPS yasintha ndondomeko yake yofuna kuti otenga nawo mbali "adziwe kusuta (kusuta kapena kusuta) chamba.
A FDA adakayikiranso mapangidwe a kafukufukuyu omwe amalola kuti azitha kudziwongolera - kutanthauza kuti otenga nawo mbali amatha kudya chamba malinga ndi zofuna zawo, koma osapitilira kuchuluka kwake, ndipo MAPS adakana kunyalanyaza mfundoyi.
Mneneri wa FDA adauza atolankhani kuti sanathe kupereka zambiri zomwe zidapangitsa kuti chivomerezo cha gawo lachiwiri chivomerezedwe, koma adawulula kuti bungweli "likuzindikira kufunikira kowonjezera chithandizo chamankhwala owonjezera matenda amisala monga pambuyo povulala. kupsinjika maganizo
Kafukufukuyu adathandizidwa ndi Michigan Veterans Cannabis Research Grants Program, yomwe imagwiritsa ntchito msonkho wa boma wa chamba kuti ipereke ndalama kwa FDA idavomereza mayeso azachipatala osachita phindu kuti "afufuze momwe chamba chachipatala chikugwirira ntchito pochiza matenda komanso kupewa kudzivulaza ku United States. Mayiko.
Akuluakulu aboma adalengeza $13 miliyoni zothandizira kafukufukuyu mu 2021, zomwe ndi gawo la ndalama zokwana $20 miliyoni. Chaka chimenecho, $ 7 miliyoni ina idaperekedwa ku Wayne State University's Community Action and Economic Opportunity Bureau, yomwe idagwirizana ndi ofufuza kuti aphunzire momwe chamba chachipatala chingathandizire matenda osiyanasiyana amisala, kuphatikiza kupsinjika kwakanthawi, nkhawa, kugona, kukhumudwa, ndi chizolowezi chofuna kudzipha.
Nthawi yomweyo, mu 2022, Michigan Cannabis Administration idaganiza zopereka $20 miliyoni chaka chimenecho ku mayunivesite awiri: University of Michigan ndi Wayne State University. Woyambayo adaganiza zophunzira kugwiritsa ntchito CBD pakuwongolera ululu, pomwe omalizawo adalandira ndalama zothandizira maphunziro awiri odziyimira pawokha: imodzi inali "mayesero oyamba osasinthika, olamulidwa, akulu akulu" omwe cholinga chake ndi kufufuza ngati kugwiritsa ntchito cannabinoids kungathandizire kudwala. omenyera nkhondo pambuyo pa zoopsa zomwe zidachitika kale (PE) therapy; Kafukufuku wina ndi momwe chamba chachipatala chimakhudzira chifukwa cha neuroinflammation ndi malingaliro ofuna kudzipha mwa omenyera nkhondo omwe ali ndi vuto la post-traumatic stress disorder.
Woyambitsa MAPS komanso purezidenti Rick Doblin adanenapo zomwe bungweli lidalengeza zakuyesa kwachipatala komwe FDA idavomereza posachedwa kuti asitikali ankhondo aku America "akufunika mwachangu chithandizo chomwe chingachepetse zizindikiro za post-traumatic stress disorder (PTSD).
MAPS ndiwonyadira kutsogolera njira yotsegulira njira zatsopano zofufuzira ndikutsutsa malingaliro achikhalidwe a FDA, "adatero. Kafukufuku wathu wa chamba chachipatala amatsutsa njira za FDA zoperekera mankhwala molingana ndi dongosolo ndi nthawi. MAPS amakana kusokoneza mapangidwe a kafukufuku kuti agwirizane ndi malingaliro a FDA, kuwonetsetsa kuti kafukufuku wa chamba azachipatala akuwonetsa momwe amagwiritsidwira ntchito m'moyo weniweni.
Kafukufuku wam'mbuyomu wa MAPS sanaphatikizepo chamba, komanso, monga dzina la bungwe limanenera, mankhwala osokoneza bongo. MAPS apanga kampani yopanga mankhwala osokoneza bongo, Lykos Therapeutics (yomwe poyamba inkadziwika kuti MAPS Philanthropy), yomwe idafunsiranso ku FDA koyambirira kwa chaka chino kuti ivomereze kugwiritsa ntchito methamphetamine (MDMA) pochiza matenda obwera pambuyo pa zoopsa.
Koma mu Ogasiti, a FDA adakana kuvomereza MDMA ngati chithandizo chothandizira. Kafukufuku wina wofalitsidwa mu Journal of Psychiatric Research anapeza kuti ngakhale zotsatira za mayesero a zachipatala ndi "zolimbikitsa," kufufuza kwina kumafunika MDMA-Aidation Therapy (MDMA-AT) isanalowe m'malo mwa njira zomwe zilipo panopa.
Akuluakulu ena azaumoyo adanenanso kuti ngakhale izi, kuyesayesa uku kukuwonetsabe kupita patsogolo kwa boma la federal. Leith J. States, yemwe ndi mkulu wa zachipatala ku Ofesi ya Mlembi Wothandizira wa Zaumoyo ku United States, anati: “Izi zikusonyeza kuti tikupita patsogolo, ndipo tikuchita zinthu pang’onopang’ono.
Kuphatikiza apo, mwezi uno, woweruza woweruza wa US Drug Enforcement Administration (DEA) anakana pempho la Veterans Action Committee (VAC) kuti atenge nawo mbali pamlandu womwe ukubwera waulamuliro wa Biden wokonzanso chamba. VAC inanena kuti lingaliroli ndi "chipongwe cha chilungamo" popeza silikuphatikiza mawu ofunikira omwe angakhudzidwe ndi kusintha kwa mfundo.
Ngakhale kuti DEA yakhazikitsa mndandanda wa mboni za okhudzidwa, VAC inanena kuti "yalephera" kukwaniritsa udindo wake wolola okhudzidwa kuti achitire umboni. Bungwe la omenyera ufulu wankhondo linanena kuti izi zitha kuwoneka chifukwa Woweruza Mulroney adayimitsa mlanduwo mpaka koyambirira kwa 2025 ndendende chifukwa DEA idapereka chidziwitso chosakwanira pamalingaliro a mboni zake zosankhidwa pakukonzanso chamba kapena chifukwa chomwe akuyenera kuwonedwa ngati okhudzidwa. .
Nthawi yomweyo, bungwe la US Congress lidapereka chigamulo chatsopano cha Senate mwezi uno wofuna kuwonetsetsa kuti asitikali akale omwe adakumana ndi mankhwala omwe angakhale oopsa pa Cold War, kuphatikiza ma hallucinogens monga LSD, ma nerve agents, ndi mpweya wa mpiru. Dongosolo loyesa mwachinsinsili lidachitika kuyambira 1948 mpaka 1975 pamalo ankhondo ku Maryland, kuphatikiza asayansi akale a Nazi omwe adapereka izi kwa asitikali aku America.
Posachedwapa, asitikali aku US adayika ndalama zokwana madola mamiliyoni ambiri kupanga mtundu watsopano wamankhwala omwe atha kupereka chithandizo chofulumira chamankhwala amisala monga mankhwala azikhalidwe zama psychedelic, koma osatulutsa zotsatira za psychedelic.
Omenyera nkhondo atenga gawo lotsogola pakuvomerezeka kwa chamba chachipatala komanso kayendetsedwe kake kakusintha mankhwala a psychedelic m'boma ndi feduro. Mwachitsanzo, koyambirira kwa chaka chino, bungwe la Veterans Service Organisation (VSO) lidalimbikitsa mamembala a Congress kuti achite kafukufuku mwachangu pazabwino zomwe zitha kuthandizidwa ndi mankhwala a psychedelic komanso chamba chachipatala.
Asanayambe pempho lomwe mabungwe monga American Iraq ndi Afghanistan Veterans Association, American Overseas War Veterans Association, American Disabled Veterans Association, ndi Disabled Soldiers Project, mabungwe ena adadzudzula Department of Veterans Affairs (VA) kuti " pang'onopang'ono" pakufufuza kwa chamba chachipatala pamsonkhano wapachaka wa Veterans Service wa chaka chatha.
Motsogozedwa ndi andale aku Republican, zoyesayesa zosintha zinthu zikuphatikizanso chiwongola dzanja chamankhwala cha psychedelic chothandizidwa ndi Republican Party ku Congress, chomwe chimayang'ana kwambiri mwayi wopezeka kwa asitikali akale, kusintha kwamaboma, komanso zokambirana zingapo pakukulitsa mwayi wopeza mankhwala osokoneza bongo a psychedelic.
Kuphatikiza apo, Congressman wa Wisconsin Republican a Derrick Van Orden wapereka chikalata cha congressional psychedelic drug bill, chomwe chawunikiridwa ndi komiti.
Van Oden ndiwonso wopereka chithandizo cha njira ziwiri zomwe cholinga chake ndi kupereka ndalama ku dipatimenti ya chitetezo (DOD) kuti ichite mayeso azachipatala pazamankhwala omwe ali ndi vuto la psychedelic kwa asitikali ogwira ntchito. Kusintha uku kwasainidwa kukhala lamulo ndi Purezidenti Joe Biden pansi pakusintha kwa 2024 National Defense Authorization Act (NDAA).
M'mwezi wa Marichi chaka chino, atsogoleri azandalama a congressional adalengezanso ndondomeko yowonongera ndalama yomwe idaphatikizirapo ndalama zokwana $ 10 miliyoni kulimbikitsa kafukufuku wamankhwala amisala.
Mu Januwale chaka chino, Dipatimenti Yowona Zankhondo Zankhondo idapereka pempho lapadera lopempha kafukufuku wozama pakugwiritsa ntchito mankhwala osokoneza bongo a psychedelic pochiza matenda obwera pambuyo povulala komanso kukhumudwa. Mwezi watha wa Okutobala, dipatimentiyi idakhazikitsa podcast yatsopano yokhudza zamtsogolo zachipatala cha akale akale, ndi gawo loyamba la mndandanda womwe umayang'ana kwambiri pakuchiritsa kwamankhwala a psychedelic.
Pa gawo la boma, bwanamkubwa wa Massachusetts adasaina chikalata mu Ogasiti chomwe chimayang'ana omenyera nkhondo, kuphatikiza makonzedwe okhazikitsa gulu logwiritsa ntchito mankhwala osokoneza bongo a psychedelic kuti liphunzire ndikupereka malingaliro pazabwino zochiritsira za zinthu monga psilocybin ndi MDMA.
Pakadali pano, ku California, opanga malamulo adasiya kuganizira za bipartisan mu Juni yomwe ikadavomereza ntchito yoyendetsa ndege yopereka chithandizo cha psilocybin kwa omenyera nkhondo komanso omwe adayankhapo mwadzidzidzi.

MJ


Nthawi yotumiza: Nov-26-2024